Menarini Biotech is a Custom Manufacturing Organization (CDMO) specialized in Process Development and GMP manufacturing of biopharmaceuticals.
2022 - 12 - 14
White paper “Application of High-Throughput methods for fast screening during Cultivation Process Development of monoclonal Antibodies” December 2022
Imma Longobardo e Meri Gabr
Development of a robust and reproducible biopharmaceutical process for production of monoclonal Antibodies (mAbs) is a critical path activity in the overall process development timeline.
A platform of fast and diagnostic analytical methods is fundamental during cultivation process development for screening of different conditions to give sufficient data related to productivity and critical quality attributes and, at the same time, to make experimentation more cost effective, on tight timelines, by saving on labor, facility space, capital, media and consumables.
An overview of analytical high-throughput approaches to support cultivation process development during screening at AMBR scale is described in this article.
